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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1H
All Species:
7.27
Human Site:
S653
Identified Species:
26.67
UniProt:
O95180
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95180
NP_001005407.1
2353
259163
S653
H
G
P
L
S
L
N
S
P
D
P
Y
E
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537016
2449
267905
G750
Q
S
P
L
S
L
R
G
P
D
P
Y
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
O88427
2365
261928
S653
H
S
P
L
S
L
G
S
P
S
P
Y
E
K
I
Rat
Rattus norvegicus
Q9EQ60
2359
261094
S653
H
S
P
L
S
L
G
S
P
R
P
Y
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414830
2380
267842
G696
V
N
S
P
V
T
L
G
T
D
S
Y
G
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
D301
D
T
T
L
N
V
T
D
T
F
D
F
K
A
Y
Tiger Blowfish
Takifugu rubipres
Q2XVR6
1719
196461
D192
K
D
P
W
N
W
L
D
F
M
V
I
S
M
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
79.9
N.A.
84.5
84.9
N.A.
N.A.
69.7
N.A.
23.7
21.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
84.2
N.A.
88.2
88.5
N.A.
N.A.
78.9
N.A.
40.2
38.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
80
80
N.A.
N.A.
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
73.3
N.A.
80
80
N.A.
N.A.
26.6
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
15
0
0
0
0
0
29
0
43
15
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
15
0
15
0
0
0
% F
% Gly:
0
15
0
0
0
0
29
29
0
0
0
0
15
0
0
% G
% His:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
58
% I
% Lys:
15
0
0
0
0
0
0
0
0
0
0
0
15
72
0
% K
% Leu:
0
0
0
72
0
58
29
0
0
0
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
15
0
% M
% Asn:
0
15
0
0
29
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
72
15
0
0
0
0
58
0
58
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
15
0
0
0
0
0
% R
% Ser:
0
43
15
0
58
0
0
43
0
15
15
0
15
0
0
% S
% Thr:
0
15
15
0
0
15
15
0
29
0
0
0
0
0
0
% T
% Val:
15
0
0
0
15
15
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
15
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
72
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _